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교수소개



식품생리활성소재 실험실

  • 권영인 (Young-In Kwon)
  • 한남대학교 식품영양학과 교수
  • 식품생리활성소재(Bioactive Food Components Lab.) 연구실 - 730104A(연구실) /730104(실험실)
  • E-mail.
    Office Tel. +82-42-629-8790
    Lab. Tel. +82-42-629-8800
    Fax +82-42-629-8789


연구분야

식품 중에 존재하는 생리활성 소재의 스크리닝, 활성물질의 분리정제, 발효 및 생물전환을 통한 생리활성 소재의 효율적인 이용방법을 개발하여 특정 생리활성이 강화된 기능성 식품 개발에 대한 연구를 수행한다.

현재 진행중인 연구는 식물과 해양생물 소재로부터 대사성 질환에 유효한 항산화, 항비만, 항당뇨, 항균, 항암활성을 가지고 있는
1) 생리활성물질의 분리 및 정제
2) 물질의 효능(In-vitro, In-vivo) 및 분자수준의 기작 규명
3) 소재의 발효 및 생물전환을 통한 생리활성의 개선, 증강 연구를 수행하고 있다.


연구논문

2015's

1. Kang BH, Racicot K, Pilketon SJ, Kwon YI, Apostolidis E. "Blueberry extract inhibits carbohydrate-hydrolyzing enzymes and these inhibitory activities are not proanthocyanidin dependent" J Korean Soc Appl Biol Chem 2015;58(1):127-136

2. Oh JB, Jo SH, Kim JS, Ha KS, Lee JY, Choi HY, Yu SY, Kwon YI, Kim YC. "Selected Tea and Tea Pomace Extracts Inhibit Intestinal α-Glucosidase Activity in vitro and Postprandial Hyperglycemia in vivo" Int J Mol Sci 2015;16(4):8811-8825

2014's

1. Li W, Sun YN, Yan XT, Yang SY, Jo SH, Kwon YI, Kim YH. "Rat Intestinal Sucrase and α-Glucosidase Inhibitory Activities of Isocoumarin and Flavonoids from the Zanthoxylum schinifolium Stems" B Korean Chem Soc 2014;35(1):316-318

2. Thao NP, Luyen BT, Tai BH, Yang SY, Jo SH, Cuong NX, Nam NH, Kwon YI, Minh CV, Kim YH. "Rat Intestinal Sucrase Inhibition of Constituent from the Roots of Rosa rugosa Thunb." Bioorg Med Chem Lett 2014;24(4):1192-1196

3. Singh K, Kafka A, Kang BH, Goundra R, Kwon YI, Apostolidis E. "In vtiro Evaluation and Determination of Responsible Fraction of Coffee Beans and Dried Sugar Beet Leaves for α-Glucosidase Inhibition" Int J Appl Res Nat Pro 2014;7(1):15-20

4. Choi EJ, Ka EH, Cho CY, Jo SH, Apostolidis E, Lee MS, Jang HD, Kwon YI. "Comparison of the Antimicrobial and Antioxidant Activities of Selected Wheat Varieties" Food Sci Biotechnol 2014;23(3):791-797

5. Thao NP, Luyen BTT, Jo SH, Hung TM, Cuong NX, Nam NH, Kwon YI, Minh CV, Kim YH. "Triterpenoid saponins from the roots of Rosa rugosa Thunb. as rat intestinal sucrase inhibitors" Arch Pharm Res 2014;37(10):1280-1285

6. Lee KH, Ha KS, Jo SH, Lee CM, Kim YC, Chung KH, Kwon YI. "Effect of Long-term Dietary Arginyl-Fructose (AF) on Hyperglycemia and HbA1c in Diabetic db/db Mice" Int J Mol Sci 2014;15(5):8352-8359

7. Jo SH, Ha KS, Lee JW, Kim YC, Apostolidis E, Kwon YI. "The Reduction Effect of Low Molecular Weight Chitosan Oligosaccharide (GO2KA1) on Postprandial Blood Glucose Levels in Healthy Individuals" Food Sci Biotechnol 2014;23(3):971-973

8. Kim JK, Jo SH, Ha KS, Kim SC, Kim YC, Apostolidis E, Kwon YI. "Effect of Long-term Supplementation of Low Molecular Weight Chitosan Oligosaccharide (GO2KA1) on Fasting Blood Glucose and HbA1c in db/db Mice Model and Elucidation of Mechanism of Action" BMC Complem Altern M 2014;14(1):272-278

9. Luyen BT, Tai BH, Thao NP, Yang SY, Cuong NM, Kwon YI, Jang HD, Kim YH. "A New Phenylpropanoid and an Alkylglycoside from Piper retrofractum Leaves with Their Antioxidant and α-Glucosidase Inhibitory Activity" Bioorg Med Chem Lett 2014;24(17):4120-4124

10. Kim HJ, Ahn HY, Kwak JH, Shin DY, Kwon YI, Oh CG, Lee JH. "The Effects of Chitosan Oligosaccharide (GO2KA1) Supplementation on Glucose Control in Subjects with Prediabetes" Food Funct 2014;5(10):2662-2669

2013's

1. Giang VH, Ban NK, Nhiem NX, Kiem PV, Minh CV, Anh HLT, Yen PH, Tai BH, Cuong NX, Nam NH, Kim SH, Kwon YI, Kim YH. "Chemical Constituents of the Morinda tomentosa Leaves and Their α-Glucosidase Inhibitory Activity" B Korean Chem Soc 2013;34(5):1555-1558

2. Jo SH, Hong SG, Jo CY, Ha KS, Kwon YI. "Enhancement of the Anti-hyperglycemic and Antioxidant Activities of Wheat by the Germination Process" Korean J Food Presev 2013;12(1):3-7

3. Jo SH, Ha KS, Moon KS, Kim JG, Oh CG, Kim YC, Apostolidis E, Kwon YI. "Molecular Weight Dependent Glucose Lowering Effect of Low Molecular Weight Chitosan Oligosaccharide (GO2KA1) on Postprandial Blood Glucose Level in SD Rats Model" Int J Mol Sci 2013;14(7)14214-14224

4. Jo SH, Cho CY, Ha KS, Choi EJ, Kang YR, Kwon YI. "The Antioxidant and Antimicrobial Activities of Extracts of Selected Barley and Wheat Inhabited in Korean Peninsula" J Kor Soc Food Sci Nutr 2013;42(7):1003-1007

5. Kim JB, Shin WS, Kwon YI, Bang BH. "Isolation and Purification of Antibacterial Components in Cortex Phellodendri" Korean J Food Nutr 2013;26(3):547-552

2012's

1. Cho CY, Choi HY, Jo SH, Ha KS, Chung JS, Jang HD, Kwon YI. "Enhancement of the Anti-hyperglycemic and Antioxidant Activities of Five Selected Beans by the Germination Process" Korean J Food Nutr 2012;25(2):246-252

2. Kim GN, Kim ES, Kwon YI, Jang HD. "Potential Mechanism of Kaempferol against Cu2+-induced Oxidative Stress through Chelating Activity and Regulation of Nuclear Factor-erythroid-2-related Factor 2 Signaling" Food Sci Biotechnol 2012;21(5):1469-1475

3. Choi HY, Ha KS, Jo SH, Ka EH, Chang HB, Kwon YI. "Antioxidant and Anti-hyperglycemic Effects of a Sanghwang Mushroom (Phellinus linteusau) Water Extract" Korean J Food Nutr 2012;25(2):239-245