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줄기세포 및 영양유전체학 실험실

  • 박은미(Eunmi Park), Ph.D.
  • 한남대학교 식품영양학과 조교수
  • 줄기세포 및 영양유전체학 연구실 730101호
  • E-mail address:
    042) 629-8793 (연구실)
    042) 629-8799 (실험실)


연구 경력 및 수상

앰디앤덜슨 암 연구소 박사 연구생: Research Assistant, The University of Texas MD Anderson Cancer Center-Science Park, Texas USA (Mentor: Dr. Yinling Hu), 03/03-08/08

하버드 의대 박사후 과정: Department of Radiation Oncology,Dana-Farber Cancer Institute Harvard Medical School, Boston MA, USA (PI:Dr. Alan D D’Andrea), 09/08-02/14

하버드의대 방문교수: Visiting Scholar, Harvard Medical School, Boston MA, USA, 07/14-08/14

ASCO Gianni Bonadonna Breast Cancer Fellowship, 09/2008

Susan G. Komen Breast Cancer Fellowship, 06/2010-02/2014

Claudia Adams Barr Award, 10/2014

Cold Spring Harbor Asia/ ISSCR meeting, Poster Award, 10/2013


관심 연구분야

1) Phytonutrients의 암세포 발생기전 및 암 예방 연구

2) 줄기세포의 self-renewal과 항산화영양소의 상관관계
- 줄기세포 self-renewal의 영향을 미치는 항산화제 스크리닝 및 기전연구
- 피부노화 예방을 위한 줄기세포 self-renewal 및 IPS 연구

3) Nutrigenomics와 chromatin remodeling

4) 암환자/Fanconi anemia의 식단관리 및 운동처방


연구활동

연구 논문

Young Eun Choi , Eunmi Park . Curcumin enhances poly (ADP-ribose) polymerase inhibitor sensitivity to chemotherapy in breast cancer cells. Journal of Nutritional Biochemistry, 2015 Accepted.
* 분야별 상위 10% 논문

Jin Ah Cho, Eunmi Park. Curcumin utilizes the Anti-inflammatory Response Pathway to Protect the Intestine against Bacterial Invasion. NRP, 2015 April.

Young Eun Choi, Eunmi Park. Ferulic acid in combination with PARP inhibitor sensitizes breast cancer cells as chemotherapeutic strategy. BBRC, 2015 March.

Youngeun Choi, Yunfeng Pan, Eunmi Park,Panagiotis A Konstantinopoulos, Subhajyoti De, Alan D'Andrea,Dipanjan Chowdhury. MicroRNAs down-regulate homologous recombination in the G1 phase of cycling cells to maintain genomic stability. E-Life, 2014.

Helena Mistry, Grace Hsieh, Sara Buhrlage, Min Huang, Eunmi Park, Gregory D. Cuny, Ilene Galinsky, Richard Stone, Nathanael Gray, Alan D. D’Andrea, Kalindi Parmar. Small molecule inhibitors of USP1 target ID1 degradation in leukemic cells. Mol Cancer Therapeutics, Oct 15, 2013

Eunmi Park, Jung Min Kim, Benjamin Primack, David M. Weinstock, Lisa A. Moreau, Kalindi Parmar, Alan D. D’Andrea. Inactivation of Uaf1 cause Homologous Recombination Defect and early embryonic lethality in mice. Molecular and Cellular Biology, Nov, 2013, Vol 22 (IF: 5.37)

  • Spotlight to November issue 22.

Yuqing Zhang, Eunmi Park, Christopher Kim, Ji-hye Paik. ZNF365 promotes stalled replication forks recovery to maintain genome stability. Cell cycle, Sep 1. 2013

Eunmi Park, Hyungjin Kim, Jung Min Kim, Benjamin Primack, Sofia Vidal-Cardenas, Ye Xu, Brendan D. Price, Alea A. Mills, Alan D. D’Andrea. FANCD2 activates transcription of TAp63 and suppresses tumorigenesis, Molecular Cell, Jun 28, 2013 (IF: 15.28)
* The paper was issued in Molecular Cell Review (Vol 52, Nov, 2013): The intertwinded roles of transcription and repair proteins.

Kevin O’conor, Donniphat D, Eunmi Park, Claudia N, Alec C Kimmerman, Alan D. D’Andrea, George-Lucian moldovan. PARI Overexpression Promotes Genomic Instability and Pancreatic Tumorigenesis. Cancer Research, April 15. 2013

Xiaojun Xia, Eunmi Park, Susan Fischer, Yinling Hu. Mouse Genetic Models Reveal Surprising Functions of IκB Kinase Alpha in Skin Development and Skin Carcinogenesis. Cancers. Feb 15. 2013

Choi JH, Lim KH, Park E, Kim JY, Choi YK, Baek KH. J Cell Biochem. 2013 Feb;114(2):303-13

Kee Y, Huang M, Chang S, Moreau L, Park E, Smith PG, D'Andrea AD. Inhibition of Nedd 8 system sensitizes cells to DNA interstrand crosslinking agents. Mol Cancer Res. 2012 Mar;10(3):369-77

Eunmi Park, Bigang Liu, Xiaojun Xia‌, Feng Zhu, Jami Willette-Brown & Yinling Hu. Role of IKKα in skin squamous cell carcinomas. Future Oncol. 2011 Jan 7(1):123-34.

Xiaojun Xia, Eunmi Park, Bigang Liu, Jami Willette-Brown, David Michell, Susan M. Fischer, Yinling Hu. Reduction of IKKα expression promotes chronic ultraviolet B exposure-induced skin inflammation and carcinogenesis. The American Journal of Pathology 2010 May. 176(5):2500-8.

Bigang Liu, Feng Zhu, Xiaojun Xia, Eunmi Park and Yinling Hu. A tale of terminal differentiation: IKKalpha, the master keratinocyte regulator. Cell Cycle 2009 Feb 15. 15;8(4):527-31.

Feng Zhu, Eunmi Park, Bigang Liu, Xiaojun Xia, Susan M Fischer, Yinling Hu. Critical role of IB kinase alpha in embryonic skin development and skin carcinogenesis. Review. Histology and Histopathology 2009 Feb;24(2):265-71.

Bigang Liu, Xiaojun Xia, Feng Zhu, Eunmi Park, Steve Carbajal, Kaoru Kiguchi, John DiGiovanni, Susan M. Fischer, Yinling Hu. IKKalpha is required to maintain skin homeostasis and prevent skin cancer. Cancer Cell, 2008 9: 14(3), 212-225.

Eunmi Park, Feng Zhu, Bigang Liu, Xiajojun Xia, Jianjun Shen, Tracie Bustos, Susan M Fischer, Yinling Hu. Reduction in I {kappa}B kinase {alpha} expression promotes the development of skin papillomas and carcinomas. Cancer Research 2007 67 (19): 9158-9168.

Bigang Liu, Eunmi Park, Feng Zhu, Tracie Bustos, Jinsong Liu, Jianjun Shen, Susan M Fischer, Yinling Hu. A critical role for I {kappa}B kinase {alpha} in the development of human and mouse squamous cell carcinomas. PNAS 2006 103: 17202-17207.

Eunmi Park, Hee-Young Paik, Joung-Soon Kim, Youg Wen. Comparative Assessments of Dietary Intake of Korean–Chinese and Koreans. Journal of the Korean Society of Dietary Culture 2000 15(5): 368-378.